Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK.

Sun, Qinghua

Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Oct 2008 - 1760-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1524-4636

10.1161/ATVBAHA.108.166967 doi


Angiotensin II--administration & dosage
Animals
Antioxidants--pharmacology
Aorta, Thoracic--drug effects
Biopterins--analogs & derivatives
Blood Pressure--drug effects
Cells, Cultured
Disease Models, Animal
Enzyme Inhibitors--pharmacology
Hypertension--chemically induced
Infusion Pumps, Implantable
Inhalation Exposure
Male
Myosin Light Chains--metabolism
NADPH Oxidases--metabolism
Nitric Oxide Synthase--metabolism
Particle Size
Particulate Matter--toxicity
Phosphorylation
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Time Factors
Vasoconstriction--drug effects
rho-Associated Kinases--antagonists & inhibitors
rhoA GTP-Binding Protein--metabolism