Inactivation of glycogen synthase kinase-3beta contributes to brain-derived neutrophic factor/TrkB-induced resistance to chemotherapy in neuroblastoma cells.

Li, Zhijie

Inactivation of glycogen synthase kinase-3beta contributes to brain-derived neutrophic factor/TrkB-induced resistance to chemotherapy in neuroblastoma cells. [electronic resource] - Molecular cancer therapeutics Dec 2007 - 3113-21 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1535-7163

10.1158/1535-7163.MCT-07-0133 doi


Antineoplastic Agents--therapeutic use
Brain-Derived Neurotrophic Factor--physiology
Cell Line, Tumor
Cisplatin--therapeutic use
Drug Resistance, Neoplasm
Etoposide--pharmacology
Flow Cytometry
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Humans
Membrane Potentials--drug effects
Neuroblastoma--drug therapy
Phosphorylation
Proto-Oncogene Proteins c-akt--metabolism
RNA, Small Interfering
Receptor, trkB--physiology