1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism.

Ohta, Akio

1,3,7-trimethylxanthine (caffeine) may exacerbate acute inflammatory liver injury by weakening the physiological immunosuppressive mechanism. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2007 - 7431-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

0022-1767

10.4049/jimmunol.179.11.7431 doi


ADP Ribose Transferases
Acute Disease
Adenosine A2 Receptor Antagonists
Animals
Bacterial Toxins
Caffeine--blood
Chemical and Drug Induced Liver Injury--immunology
Disease Models, Animal
Dose-Response Relationship, Drug
Exotoxins
Female
Liver--drug effects
Mice
Mice, Inbred C57BL
Mice, Knockout
Phosphodiesterase Inhibitors--blood
Receptor, Adenosine A2A--genetics
Virulence Factors
Pseudomonas aeruginosa Exotoxin A