Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer.
Shi, Yue Y
Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer. [electronic resource] - Breast cancer research and treatment Nov 2006 - 33-47 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-006-9232-x doi
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Breast Neoplasms--enzymology
Cell Cycle Proteins--metabolism
Cell Line, Transformed
Cell Line, Tumor
Dual Specificity Phosphatase 1
Female
Humans
Immediate-Early Proteins--metabolism
Phosphoprotein Phosphatases--metabolism
Protease Inhibitors--pharmacology
Protein Phosphatase 1
Protein Tyrosine Phosphatases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Pyrazines--pharmacology
p38 Mitogen-Activated Protein Kinases--drug effects
Proteasome inhibitors induce a p38 mitogen-activated protein kinase (MAPK)-dependent anti-apoptotic program involving MAPK phosphatase-1 and Akt in models of breast cancer. [electronic resource] - Breast cancer research and treatment Nov 2006 - 33-47 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
0167-6806
10.1007/s10549-006-9232-x doi
Apoptosis--drug effects
Boronic Acids--pharmacology
Bortezomib
Breast Neoplasms--enzymology
Cell Cycle Proteins--metabolism
Cell Line, Transformed
Cell Line, Tumor
Dual Specificity Phosphatase 1
Female
Humans
Immediate-Early Proteins--metabolism
Phosphoprotein Phosphatases--metabolism
Protease Inhibitors--pharmacology
Protein Phosphatase 1
Protein Tyrosine Phosphatases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Pyrazines--pharmacology
p38 Mitogen-Activated Protein Kinases--drug effects