Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner.

Liu, Junling

Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. [electronic resource] - Blood Oct 2005 - 2750-6 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0006-4971

10.1182/blood-2005-04-1667 doi


Adenosine Triphosphate--metabolism
Animals
Blood Platelets--drug effects
CD36 Antigens--metabolism
Crotalid Venoms--pharmacology
Enzyme Precursors--deficiency
Intracellular Signaling Peptides and Proteins
Mice
Mice, Knockout
Phosphatidylinositol 3-Kinases--metabolism
Phospholipase C gamma
Platelet Aggregation--drug effects
Platelet Glycoprotein GPIIb-IIIa Complex--metabolism
Platelet Glycoprotein GPIb-IX Complex--metabolism
Protein Kinase C--metabolism
Protein Kinase Inhibitors--pharmacology
Protein-Tyrosine Kinases--deficiency
Proto-Oncogene Proteins pp60(c-src)--antagonists & inhibitors
Receptors, Fc--metabolism
Signal Transduction--drug effects
Syk Kinase
Thromboxane A2--metabolism
Type C Phospholipases--deficiency
src-Family Kinases--metabolism
von Willebrand Factor--pharmacology