Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease.

Goffredo, Donato

Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease. [electronic resource] - Pharmacological research Aug 2005 - 140-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1043-6618

10.1016/j.phrs.2005.01.006 doi


Animals
Apoptosis Regulatory Proteins
Brain--metabolism
Carrier Proteins--metabolism
Cell Line
Cell Survival
Cyclosporine--pharmacology
Cytosol--metabolism
High-Temperature Requirement A Serine Peptidase 2
Humans
Huntingtin Protein
Huntington Disease--genetics
Inhibitor of Apoptosis Proteins
Intracellular Signaling Peptides and Proteins
Mice
Mitochondria--metabolism
Mitochondrial Proteins--metabolism
Mutation
Nerve Tissue Proteins--genetics
Nuclear Proteins--genetics
Proteins--metabolism
Pyrimidinones--pharmacology
Serine Endopeptidases--metabolism
Thiones--pharmacology
Ubiquitin-Protein Ligases
X-Linked Inhibitor of Apoptosis Protein