Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide.
Jiang, Xiuxian
Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide. [electronic resource] - Molecular cancer therapeutics Oct 2004 - 1221-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-7163
Antineoplastic Agents--pharmacology
Catalytic Domain
Cell Line, Tumor
Checkpoint Kinase 1
Crystallography, X-Ray
Cysteine--chemistry
DNA Damage
Dose-Response Relationship, Drug
G2 Phase
Glutamine--chemistry
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Imidazoles--pharmacology
Indoles--antagonists & inhibitors
Inhibitory Concentration 50
Maleimides--antagonists & inhibitors
Models, Chemical
Models, Molecular
Nitrogen--chemistry
Phenotype
Protein Binding
Protein Kinase C--metabolism
Protein Kinase C beta
Protein Kinases--metabolism
Protein Structure, Tertiary
Time Factors
Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide. [electronic resource] - Molecular cancer therapeutics Oct 2004 - 1221-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-7163
Antineoplastic Agents--pharmacology
Catalytic Domain
Cell Line, Tumor
Checkpoint Kinase 1
Crystallography, X-Ray
Cysteine--chemistry
DNA Damage
Dose-Response Relationship, Drug
G2 Phase
Glutamine--chemistry
Glycogen Synthase Kinase 3--metabolism
Glycogen Synthase Kinase 3 beta
Humans
Imidazoles--pharmacology
Indoles--antagonists & inhibitors
Inhibitory Concentration 50
Maleimides--antagonists & inhibitors
Models, Chemical
Models, Molecular
Nitrogen--chemistry
Phenotype
Protein Binding
Protein Kinase C--metabolism
Protein Kinase C beta
Protein Kinases--metabolism
Protein Structure, Tertiary
Time Factors