Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia.

Rogoza, Raina M

Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia. [electronic resource] - Synapse (New York, N.Y.) Dec 2004 - 156-63 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0887-4476

10.1002/syn.20078 doi


Analysis of Variance
Animals
Antipsychotic Agents--toxicity
Apomorphine--pharmacology
Behavior, Animal
Binding Sites
Corpus Striatum--drug effects
Cyclic N-Oxides
Disease Models, Animal
Dopamine Agonists--pharmacology
Drug Interactions
Dyskinesia, Drug-Induced--complications
Electron Spin Resonance Spectroscopy
Haloperidol--toxicity
Humans
Male
Mastication--drug effects
Motor Activity--drug effects
Movement Disorders--etiology
Neuroprotective Agents--therapeutic use
Nitrogen Oxides--therapeutic use
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species--metabolism
Receptors, Dopamine D2--physiology