Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance.

Michallet, Marie-Cécile

Cathepsin-dependent apoptosis triggered by supraoptimal activation of T lymphocytes: a possible mechanism of high dose tolerance. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) May 2004 - 5405-14 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.172.9.5405 doi


Amino Acid Chloromethyl Ketones--pharmacology
Apoptosis--immunology
CD28 Antigens--pharmacology
Caspase Inhibitors
Catalysis
Cathepsin B--antagonists & inhibitors
Cathepsin L
Cathepsins--antagonists & inhibitors
Cell Death--immunology
Cell Differentiation--immunology
Cells, Cultured
Cysteine Endopeptidases
Cysteine Proteinase Inhibitors--pharmacology
Cytochromes c--metabolism
Cytosol--enzymology
DNA Fragmentation--drug effects
Dose-Response Relationship, Immunologic
G1 Phase--immunology
Humans
Intracellular Membranes--enzymology
Lymphocyte Activation--immunology
Lysosomes--enzymology
Muromonab-CD3--pharmacology
Permeability
S Phase--immunology
T-Lymphocytes--cytology
Tetradecanoylphorbol Acetate--pharmacology