Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication.
Hwang, Seongwoo
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. [electronic resource] - The Journal of biological chemistry Oct 2003 - 39092-103 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M301749200 doi
Animals
Antiviral Agents--pharmacology
Automation
Carbamates--chemistry
Cells, Cultured
Chromatography, Gas
Dose-Response Relationship, Drug
Fluorescence Resonance Energy Transfer
Gene Products, tat--chemistry
HIV-1--chemistry
HeLa Cells
Humans
Ligands
Mice
Models, Biological
Models, Chemical
Models, Statistical
Nucleic Acid Conformation
Oligopeptides--chemistry
Peptide Library
Protein Binding
RNA--chemistry
RNA-Directed DNA Polymerase--metabolism
Structure-Activity Relationship
Transcriptional Activation
tat Gene Products, Human Immunodeficiency Virus
Discovery of a small molecule Tat-trans-activation-responsive RNA antagonist that potently inhibits human immunodeficiency virus-1 replication. [electronic resource] - The Journal of biological chemistry Oct 2003 - 39092-103 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M301749200 doi
Animals
Antiviral Agents--pharmacology
Automation
Carbamates--chemistry
Cells, Cultured
Chromatography, Gas
Dose-Response Relationship, Drug
Fluorescence Resonance Energy Transfer
Gene Products, tat--chemistry
HIV-1--chemistry
HeLa Cells
Humans
Ligands
Mice
Models, Biological
Models, Chemical
Models, Statistical
Nucleic Acid Conformation
Oligopeptides--chemistry
Peptide Library
Protein Binding
RNA--chemistry
RNA-Directed DNA Polymerase--metabolism
Structure-Activity Relationship
Transcriptional Activation
tat Gene Products, Human Immunodeficiency Virus