Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand.
Luo, Bing-Hao
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2003 - 2403-8 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.0438060100 doi
Animals
CHO Cells
Cell Line
Cricetinae
DNA, Complementary--metabolism
Dose-Response Relationship, Drug
Flow Cytometry
Genetic Linkage
Glycosylation
Humans
Integrin alphaVbeta3--chemistry
Integrins--chemistry
Ligands
Models, Molecular
Mutation
Phenotype
Plasmids--metabolism
Polysaccharides--chemistry
Protein Binding
Protein Conformation
Protein Structure, Tertiary
Transfection
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2003 - 2403-8 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0027-8424
10.1073/pnas.0438060100 doi
Animals
CHO Cells
Cell Line
Cricetinae
DNA, Complementary--metabolism
Dose-Response Relationship, Drug
Flow Cytometry
Genetic Linkage
Glycosylation
Humans
Integrin alphaVbeta3--chemistry
Integrins--chemistry
Ligands
Models, Molecular
Mutation
Phenotype
Plasmids--metabolism
Polysaccharides--chemistry
Protein Binding
Protein Conformation
Protein Structure, Tertiary
Transfection