Paralytic autoimmune myositis develops in nonobese diabetic mice made Th1 cytokine-deficient by expression of an IFN-gamma receptor beta-chain transgene.

Serreze, David V

Paralytic autoimmune myositis develops in nonobese diabetic mice made Th1 cytokine-deficient by expression of an IFN-gamma receptor beta-chain transgene. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2003 - 2742-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.170.5.2742 doi


Adoptive Transfer
Animals
CD8-Positive T-Lymphocytes--immunology
Cell Movement--genetics
Cytokines--deficiency
Diabetes Mellitus, Type 1--genetics
Female
Gene Expression Regulation--immunology
Interferon-gamma--antagonists & inhibitors
Kinetics
Macrophages--pathology
Mice
Mice, Inbred C57BL
Mice, Inbred NOD
Mice, SCID
Mice, Transgenic
Nervous System Autoimmune Disease, Experimental--genetics
Paralysis--genetics
Receptors, Interferon--biosynthesis
Sex Characteristics
Spleen--immunology
Th1 Cells--immunology
Transgenes--immunology
Tumor Necrosis Factor-alpha--antagonists & inhibitors
Interferon gamma Receptor