The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter.

Ventura, Andrea

The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter. [electronic resource] - The Journal of biological chemistry Jun 2002 - 22370-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M200280200 doi


3T3 Cells
Adaptor Proteins, Signal Transducing
Adaptor Proteins, Vesicular Transport
Animals
Base Sequence
Cell Line
Cell Lineage
Cytosine--metabolism
Gene Silencing
Histone Deacetylases--metabolism
Histones--metabolism
Humans
Hydroxamic Acids--pharmacology
Luciferases--metabolism
Methylation
Mice
Models, Genetic
Molecular Sequence Data
Plasmids--metabolism
Promoter Regions, Genetic
Protein Isoforms
Protein Structure, Tertiary
Proteins--genetics
RNA, Messenger--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Ribonucleases--metabolism
Shc Signaling Adaptor Proteins
Src Homology 2 Domain-Containing, Transforming Protein 1
Time Factors
Transcription, Genetic
Transfection