Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.

Raffini, Leslie J

Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2002 - 4568-73 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.062066799 doi


Base Sequence
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 4
Cloning, Molecular
Cyclin-Dependent Kinase 6
Cyclin-Dependent Kinases
DNA-Binding Proteins--genetics
Female
Gene Rearrangement
Histone-Lysine N-Methyltransferase
Humans
Molecular Sequence Data
Myeloid-Lymphoid Leukemia Protein
Nuclear Proteins--genetics
Polymerase Chain Reaction--methods
Protein Serine-Threonine Kinases--genetics
Proto-Oncogenes
Transcription Factors
Transcriptional Elongation Factors
Translocation, Genetic