Decreased expression of the GHRH receptor gene due to a mutation in a Pit-1 binding site.

Salvatori, Roberto

Decreased expression of the GHRH receptor gene due to a mutation in a Pit-1 binding site. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Mar 2002 - 450-8 p. digital

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0888-8809

10.1210/mend.16.3.0785 doi


Animals
Base Sequence
Binding Sites
CHO Cells
Cell Line
Child, Preschool
Cricetinae
Cyclic AMP--pharmacology
DNA Mutational Analysis
DNA-Binding Proteins--metabolism
Gene Expression
Glutamic Acid
Growth Hormone-Releasing Hormone--pharmacology
Heterozygote
Human Growth Hormone--deficiency
Humans
Luciferases--genetics
Lysine
Male
Mutation
Mutation, Missense
Pituitary Gland--metabolism
Promoter Regions, Genetic
Rats
Receptors, Neuropeptide--chemistry
Receptors, Pituitary Hormone-Regulating Hormone--chemistry
Transcription Factor Pit-1
Transcription Factors--metabolism
Transfection