NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death.

Zheng, Y

NF-kappa B RelA (p65) is essential for TNF-alpha-induced fas expression but dispensable for both TCR-induced expression and activation-induced cell death. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Apr 2001 - 4949-57 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.166.8.4949 doi


3T3 Cells
Animals
Apoptosis--drug effects
Base Sequence
Binding Sites--genetics
CD4-Positive T-Lymphocytes--cytology
Cells, Cultured
Cloning, Molecular
Down-Regulation--genetics
Fas Ligand Protein
Fibroblasts--metabolism
Humans
Jurkat Cells
Ligands
Lymphocyte Activation--drug effects
Membrane Glycoproteins--biosynthesis
Mice
Mice, Inbred C57BL
Molecular Sequence Data
NF-kappa B--deficiency
NF-kappa B p50 Subunit
Phytohemagglutinins--pharmacology
Promoter Regions, Genetic--immunology
Proto-Oncogene Proteins c-rel--deficiency
Receptors, Antigen, T-Cell--physiology
Tetradecanoylphorbol Acetate--pharmacology
Transcription Factor RelA
Tumor Necrosis Factor-alpha--physiology
fas Receptor--biosynthesis