Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

Baker, B M

Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling. [electronic resource] - Immunity Oct 2000 - 475-84 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1074-7613

10.1016/s1074-7613(00)00047-9 doi


Alanine--metabolism
Amino Acid Substitution--immunology
Cells, Cultured
Crystallography, X-Ray
Cytotoxicity Tests, Immunologic
Gene Products, tax--chemistry
Glycine--metabolism
HLA-A2 Antigen--metabolism
Humans
Ligands
Peptides--chemistry
Proline--metabolism
Protein Binding--immunology
Protein Folding
Receptors, Antigen, T-Cell, alpha-beta--agonists
Sarcosine--metabolism
Signal Transduction--immunology
T-Lymphocytes, Cytotoxic--immunology
Thermodynamics
Ultracentrifugation--methods
Water