Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells.
Shao, J
Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells. [electronic resource] - Oncogene Feb 2000 - 726-36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0950-9232
10.1038/sj.onc.1203383 doi
Adenocarcinoma--genetics
Adenoviruses, Human--genetics
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Apoptosis--drug effects
Aspirin--pharmacology
Cell Nucleus--metabolism
Colonic Neoplasms--genetics
Cytomegalovirus--genetics
DNA-Binding Proteins--biosynthesis
Gene Expression Regulation--drug effects
Genes, p53
Genetic Vectors--genetics
Humans
I-kappa B Proteins
NF-KappaB Inhibitor alpha
NF-kappa B--metabolism
Neoplasm Proteins--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic--drug effects
Tumor Cells, Cultured
Tumor Suppressor Protein p53--biosynthesis
Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells. [electronic resource] - Oncogene Feb 2000 - 726-36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0950-9232
10.1038/sj.onc.1203383 doi
Adenocarcinoma--genetics
Adenoviruses, Human--genetics
Anti-Inflammatory Agents, Non-Steroidal--pharmacology
Apoptosis--drug effects
Aspirin--pharmacology
Cell Nucleus--metabolism
Colonic Neoplasms--genetics
Cytomegalovirus--genetics
DNA-Binding Proteins--biosynthesis
Gene Expression Regulation--drug effects
Genes, p53
Genetic Vectors--genetics
Humans
I-kappa B Proteins
NF-KappaB Inhibitor alpha
NF-kappa B--metabolism
Neoplasm Proteins--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic--drug effects
Tumor Cells, Cultured
Tumor Suppressor Protein p53--biosynthesis