Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. [electronic resource]
Producer: 19990212Description: 1190-201 p. digitalISSN:- 0270-7306
- Base Sequence
- CDC2-CDC28 Kinases
- Cell Cycle
- Cell Cycle Proteins
- Cell-Free System
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Cyclins -- metabolism
- Cysteine Endopeptidases -- metabolism
- Enzyme Inhibitors -- pharmacology
- G1 Phase
- HeLa Cells
- Humans
- In Vitro Techniques
- Microtubule-Associated Proteins -- genetics
- Multienzyme Complexes -- metabolism
- Oligonucleotide Probes -- genetics
- Proteasome Endopeptidase Complex
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Recombinant Proteins -- genetics
- S Phase
- Tumor Suppressor Proteins
- Ubiquitins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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