Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome.

Nguyen, H

Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome. [electronic resource] - Molecular and cellular biology Feb 1999 - 1190-201 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.19.2.1190 doi


Base Sequence
CDC2-CDC28 Kinases
Cell Cycle
Cell Cycle Proteins
Cell-Free System
Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinase Inhibitor p27
Cyclin-Dependent Kinases--antagonists & inhibitors
Cyclins--metabolism
Cysteine Endopeptidases--metabolism
Enzyme Inhibitors--pharmacology
G1 Phase
HeLa Cells
Humans
In Vitro Techniques
Microtubule-Associated Proteins--genetics
Multienzyme Complexes--metabolism
Oligonucleotide Probes--genetics
Proteasome Endopeptidase Complex
Protein Serine-Threonine Kinases--antagonists & inhibitors
Recombinant Proteins--genetics
S Phase
Tumor Suppressor Proteins
Ubiquitins--metabolism