The antiproliferative and cell cycle effects of 5,6,7, 8-tetrahydro-N5,N10-carbonylfolic acid, an inhibitor of methylenetetrahydrofolate dehydrogenase, are potentiated by hypoxanthine. [electronic resource]
Producer: 19981105Description: 315-21 p. digitalISSN:- 0022-3565
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Deoxyadenine Nucleotides -- metabolism
- Drug Synergism
- Enzyme Inhibitors -- pharmacology
- Folic Acid -- analogs & derivatives
- Humans
- Hypoxanthine -- pharmacology
- Methylenetetrahydrofolate Dehydrogenase (NADP) -- antagonists & inhibitors
- Thymine Nucleotides -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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