Substituent effects on the binding of phenols to the D38N mutant of 3-oxo-delta5-steroid isomerase. A probe for the nature of hydrogen bonding to the intermediate. [electronic resource]
Producer: 19980213Description: 700-5 p. digitalISSN:- 0006-2960
- Anions
- Aspartic Acid -- genetics
- Binding Sites
- Hydrogen Bonding
- Models, Chemical
- Molecular Conformation
- Molecular Probes
- Mutation
- Nuclear Magnetic Resonance, Biomolecular
- Phenols -- metabolism
- Spectrometry, Fluorescence
- Steroid Isomerases -- genetics
- Steroids -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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