Substituent effects on the binding of phenols to the D38N mutant of 3-oxo-delta5-steroid isomerase. A probe for the nature of hydrogen bonding to the intermediate.
Petrounia, I P
Substituent effects on the binding of phenols to the D38N mutant of 3-oxo-delta5-steroid isomerase. A probe for the nature of hydrogen bonding to the intermediate. [electronic resource] - Biochemistry Jan 1998 - 700-5 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi972262s doi
Anions
Aspartic Acid--genetics
Binding Sites
Hydrogen Bonding
Models, Chemical
Molecular Conformation
Molecular Probes
Mutation
Nuclear Magnetic Resonance, Biomolecular
Phenols--metabolism
Spectrometry, Fluorescence
Steroid Isomerases--genetics
Steroids--metabolism
Structure-Activity Relationship
Substituent effects on the binding of phenols to the D38N mutant of 3-oxo-delta5-steroid isomerase. A probe for the nature of hydrogen bonding to the intermediate. [electronic resource] - Biochemistry Jan 1998 - 700-5 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0006-2960
10.1021/bi972262s doi
Anions
Aspartic Acid--genetics
Binding Sites
Hydrogen Bonding
Models, Chemical
Molecular Conformation
Molecular Probes
Mutation
Nuclear Magnetic Resonance, Biomolecular
Phenols--metabolism
Spectrometry, Fluorescence
Steroid Isomerases--genetics
Steroids--metabolism
Structure-Activity Relationship