Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract. [electronic resource]
Producer: 19960905Description: 442-9 p. digitalISSN:- 1061-4036
- Animals
- Apoptosis
- Caspase 3
- Caspases
- Cell Line
- Chlorocebus aethiops
- Cysteine Endopeptidases -- metabolism
- Humans
- Huntingtin Protein
- Huntington Disease -- physiopathology
- Kinetics
- Nerve Tissue Proteins -- metabolism
- Nuclear Proteins -- metabolism
- Peptides -- chemistry
- Recombinant Proteins
- Structure-Activity Relationship
- Substrate Specificity
- Transfection
- Trinucleotide Repeats
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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