The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity. [electronic resource]
Producer: 19960813Description: 1429-35 p. digitalISSN:- 0270-9139
- Aged
- Aged, 80 and over
- Alanine Transaminase -- blood
- Alzheimer Disease -- drug therapy
- Breath Tests
- Caffeine -- pharmacokinetics
- Cholinesterase Inhibitors -- adverse effects
- Cytochrome P-450 CYP1A2
- Cytochrome P-450 Enzyme System -- metabolism
- Female
- Humans
- Liver -- drug effects
- Male
- Middle Aged
- Oxidoreductases -- metabolism
- Tacrine -- adverse effects
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Publication Type: Clinical Trial; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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