The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity.

Fontana, R J

The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity. [electronic resource] - Hepatology (Baltimore, Md.) Jun 1996 - 1429-35 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-9139

10.1002/hep.510230619 doi


Aged
Aged, 80 and over
Alanine Transaminase--blood
Alzheimer Disease--drug therapy
Breath Tests
Caffeine--pharmacokinetics
Cholinesterase Inhibitors--adverse effects
Cytochrome P-450 CYP1A2
Cytochrome P-450 Enzyme System--metabolism
Female
Humans
Liver--drug effects
Male
Middle Aged
Oxidoreductases--metabolism
Tacrine--adverse effects