Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. [electronic resource]
Producer: 19940308Description: 878-82 p. digitalISSN:- 0027-8424
- Amino Acid Sequence
- Animals
- Calcium Channel Blockers -- isolation & purification
- Calcium Channels -- classification
- Cerebellum -- drug effects
- Chick Embryo
- Elapid Venoms -- genetics
- Elapidae
- In Vitro Techniques
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Mice, Neurologic Mutants
- Molecular Sequence Data
- Neurons -- drug effects
- Rats
- Trypsin Inhibitor, Kunitz Soybean -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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