Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons.
Schweitz, H
Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Feb 1994 - 878-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.91.3.878 doi
Amino Acid Sequence
Animals
Calcium Channel Blockers--isolation & purification
Calcium Channels--classification
Cerebellum--drug effects
Chick Embryo
Elapid Venoms--genetics
Elapidae
In Vitro Techniques
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Neurologic Mutants
Molecular Sequence Data
Neurons--drug effects
Rats
Trypsin Inhibitor, Kunitz Soybean--genetics
Calcicludine, a venom peptide of the Kunitz-type protease inhibitor family, is a potent blocker of high-threshold Ca2+ channels with a high affinity for L-type channels in cerebellar granule neurons. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Feb 1994 - 878-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.91.3.878 doi
Amino Acid Sequence
Animals
Calcium Channel Blockers--isolation & purification
Calcium Channels--classification
Cerebellum--drug effects
Chick Embryo
Elapid Venoms--genetics
Elapidae
In Vitro Techniques
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Neurologic Mutants
Molecular Sequence Data
Neurons--drug effects
Rats
Trypsin Inhibitor, Kunitz Soybean--genetics