The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM). [electronic resource]
Producer: 19940526Description: 12240-7 p. digitalISSN:- 0021-9258
- Amino Acid Sequence
- Animals
- Aspartic Acid Endopeptidases -- biosynthesis
- Cell Line
- Chlorocebus aethiops
- Furin
- Gene Products, env -- isolation & purification
- HIV Envelope Protein gp120 -- biosynthesis
- HIV Envelope Protein gp160
- HIV Envelope Protein gp41 -- biosynthesis
- HIV-1 -- metabolism
- Humans
- Kinetics
- Lymphocytes -- drug effects
- Molecular Sequence Data
- Oligopeptides -- chemical synthesis
- Proprotein Convertases
- Protease Inhibitors -- chemical synthesis
- Protein Precursors -- isolation & purification
- Protein Processing, Post-Translational
- Substrate Specificity
- Subtilisins -- biosynthesis
- Tetradecanoylphorbol Acetate -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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