The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM).

Decroly, E

The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM). [electronic resource] - The Journal of biological chemistry Apr 1994 - 12240-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258


Amino Acid Sequence
Animals
Aspartic Acid Endopeptidases--biosynthesis
Cell Line
Chlorocebus aethiops
Furin
Gene Products, env--isolation & purification
HIV Envelope Protein gp120--biosynthesis
HIV Envelope Protein gp160
HIV Envelope Protein gp41--biosynthesis
HIV-1--metabolism
Humans
Kinetics
Lymphocytes--drug effects
Molecular Sequence Data
Oligopeptides--chemical synthesis
Proprotein Convertases
Protease Inhibitors--chemical synthesis
Protein Precursors--isolation & purification
Protein Processing, Post-Translational
Substrate Specificity
Subtilisins--biosynthesis
Tetradecanoylphorbol Acetate--pharmacology