All-trans retinoic acid exerts selective anti-FLT3-ITD acute myeloid leukemia efficacy through downregulating Chk1 kinase. [electronic resource]
Producer: 20201005Description: 130-138 p. digitalISSN:- 1872-7980
- Adult
- Aged
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Checkpoint Kinase 1 -- antagonists & inhibitors
- Child, Preschool
- DNA Damage -- drug effects
- DNA Repair -- drug effects
- Down-Regulation -- drug effects
- Drug Synergism
- Gene Expression Regulation, Leukemic -- drug effects
- Humans
- Irinotecan -- pharmacology
- Leukemia, Myeloid, Acute -- blood
- Male
- Mice
- Middle Aged
- Mitosis -- drug effects
- Primary Cell Culture
- Protein Kinase Inhibitors -- pharmacology
- Tandem Repeat Sequences -- genetics
- Topoisomerase I Inhibitors -- pharmacology
- Tretinoin -- pharmacology
- Xenograft Model Antitumor Assays
- fms-Like Tyrosine Kinase 3 -- genetics
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.