Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache. [electronic resource]
Producer: 20200103Description: 4253 p. digitalISSN:- 2041-1723
- Animals
- Calcitonin Gene-Related Peptide -- metabolism
- Cell Degranulation -- physiology
- Cells, Cultured
- Female
- Headache Disorders, Secondary -- chemically induced
- Hyperalgesia -- physiopathology
- Male
- Mast Cells -- pathology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Migraine Disorders -- pathology
- NAV1.9 Voltage-Gated Sodium Channel -- genetics
- Neurons, Afferent -- drug effects
- Nitric Oxide -- metabolism
- Nociceptors -- physiology
- Pain -- physiopathology
- Prescription Drug Overuse -- adverse effects
- Tryptamines -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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