Rapid Screen for Tyrosine Kinase Inhibitor Resistance Mutations and Substrate Specificity. [electronic resource]
Producer: 20200406Description: 1888-1895 p. digitalISSN:- 1554-8937
- Antibodies -- chemistry
- Cell Adhesion Molecules -- immunology
- Dasatinib -- pharmacology
- Drug Resistance -- physiology
- Flow Cytometry -- methods
- Fluorescent Dyes -- chemistry
- High-Throughput Screening Assays -- methods
- Humans
- Imidazoles -- pharmacology
- Machine Learning
- Mutation
- Phosphorylation -- drug effects
- Proof of Concept Study
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-abl -- antagonists & inhibitors
- Pyridazines -- pharmacology
- Recombinant Fusion Proteins -- immunology
- Saccharomyces cerevisiae -- chemistry
- Saccharomyces cerevisiae Proteins -- immunology
- Substrate Specificity
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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