RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. [electronic resource]
Producer: 20201015ISSN:- 2379-3708
- Animals
- Antineoplastic Agents, Immunological -- pharmacology
- Biomarkers, Tumor -- analysis
- Cell Proliferation -- drug effects
- Cetuximab -- pharmacology
- Clinical Trials as Topic
- Colorectal Neoplasms -- drug therapy
- Computational Biology
- DNA-Binding Proteins -- analysis
- Datasets as Topic
- Disease Models, Animal
- Disease Progression
- Disease-Free Survival
- ErbB Receptors -- antagonists & inhibitors
- Guanine Nucleotide Exchange Factors -- analysis
- Humans
- Kaplan-Meier Estimate
- Mice
- Mice, Knockout
- Primary Cell Culture
- Prognosis
- Signal Transduction -- drug effects
- Spheroids, Cellular
- Tumor Cells, Cultured
- Tumor Suppressor Proteins -- analysis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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