RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Gbenedio, Oghenekevwe M
RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. [electronic resource] - JCI insight 06 2019
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2379-3708
10.1172/jci.insight.127552 doi
Animals
Antineoplastic Agents, Immunological--pharmacology
Biomarkers, Tumor--analysis
Cell Proliferation--drug effects
Cetuximab--pharmacology
Clinical Trials as Topic
Colorectal Neoplasms--drug therapy
Computational Biology
DNA-Binding Proteins--analysis
Datasets as Topic
Disease Models, Animal
Disease Progression
Disease-Free Survival
ErbB Receptors--antagonists & inhibitors
Guanine Nucleotide Exchange Factors--analysis
Humans
Kaplan-Meier Estimate
Mice
Mice, Knockout
Primary Cell Culture
Prognosis
Signal Transduction--drug effects
Spheroids, Cellular
Tumor Cells, Cultured
Tumor Suppressor Proteins--analysis
RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. [electronic resource] - JCI insight 06 2019
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2379-3708
10.1172/jci.insight.127552 doi
Animals
Antineoplastic Agents, Immunological--pharmacology
Biomarkers, Tumor--analysis
Cell Proliferation--drug effects
Cetuximab--pharmacology
Clinical Trials as Topic
Colorectal Neoplasms--drug therapy
Computational Biology
DNA-Binding Proteins--analysis
Datasets as Topic
Disease Models, Animal
Disease Progression
Disease-Free Survival
ErbB Receptors--antagonists & inhibitors
Guanine Nucleotide Exchange Factors--analysis
Humans
Kaplan-Meier Estimate
Mice
Mice, Knockout
Primary Cell Culture
Prognosis
Signal Transduction--drug effects
Spheroids, Cellular
Tumor Cells, Cultured
Tumor Suppressor Proteins--analysis