PARP Inhibitor Protects Against Chronic Hypoxia/Reoxygenation-Induced Retinal Injury by Regulation of MAPKs, HIF1α, Nrf2, and NFκB. [electronic resource]
Producer: 20190920Description: 1478-1490 p. digitalISSN:- 1552-5783
- Animals
- Chronic Disease
- Cytokines -- metabolism
- Disease Models, Animal
- Fluorescent Antibody Technique, Indirect
- Hypoxia -- complications
- Hypoxia-Inducible Factor 1, alpha Subunit -- metabolism
- Immunoblotting
- Intercellular Signaling Peptides and Proteins -- metabolism
- Male
- NF-E2-Related Factor 2 -- metabolism
- NF-kappa B -- metabolism
- Oxidative Stress
- Oxygen -- toxicity
- Phosphorylation
- Phthalazines -- therapeutic use
- Piperazines -- therapeutic use
- Poly (ADP-Ribose) Polymerase-1 -- antagonists & inhibitors
- Poly(ADP-ribose) Polymerase Inhibitors -- therapeutic use
- Rats
- Rats, Wistar
- Reactive Oxygen Species -- metabolism
- Reperfusion Injury -- metabolism
- Retinal Diseases -- metabolism
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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