Elevated MeCP2 in Mice Causes Neurodegeneration Involving Tau Dysregulation and Excitotoxicity: Implications for the Understanding and Treatment of MeCP2 Triplication Syndrome. [electronic resource]
Producer: 20190118Description: 9057-9074 p. digitalISSN:- 1559-1182
- Animals
- Apoptosis -- drug effects
- Astrocytes -- drug effects
- Brain -- metabolism
- Caspase 3 -- metabolism
- Culture Media, Conditioned -- pharmacology
- Female
- Gene Expression Regulation -- drug effects
- Male
- Methyl-CpG-Binding Protein 2 -- metabolism
- Mice, Transgenic
- Models, Biological
- Nerve Degeneration -- genetics
- Nerve Tissue Proteins -- metabolism
- Neurons -- drug effects
- Neurotoxins -- toxicity
- RNA, Messenger -- genetics
- Spinal Cord -- metabolism
- Syndrome
- Up-Regulation -- drug effects
- tau Proteins -- metabolism
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Publication Type: Journal Article
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