Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells. [electronic resource]
Producer: 20181109Description: 330-343 p. digitalISSN:- 1521-4141
- Aged
- Aged, 80 and over
- Apoptosis
- CD55 Antigens -- metabolism
- Calcineurin Inhibitors -- adverse effects
- Cell Line
- Cell Survival
- Complement Membrane Attack Complex -- metabolism
- Complement System Proteins -- metabolism
- Cyclosporine -- adverse effects
- Drug-Related Side Effects and Adverse Reactions -- metabolism
- Female
- Gene Expression Regulation
- Graft Rejection -- metabolism
- Humans
- Kidney Diseases -- metabolism
- Kidney Transplantation
- Kidney Tubules -- drug effects
- MAP Kinase Signaling System
- Male
- Membrane Cofactor Protein -- metabolism
- Middle Aged
- Phosphorylation
- RNA, Small Interfering -- genetics
- Suppressor of Cytokine Signaling 3 Protein -- genetics
- Tacrolimus -- adverse effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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