Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. [electronic resource]
Producer: 20171025Description: 28-40 p. digitalISSN:- 1096-0333
- Animals
- Aryl Hydrocarbon Hydroxylases -- genetics
- Circadian Rhythm -- drug effects
- Circadian Rhythm Signaling Peptides and Proteins -- genetics
- Cytochrome P-450 CYP2B6 -- genetics
- Cytochrome P-450 Enzyme System -- deficiency
- Cytochrome P450 Family 2 -- genetics
- Dose-Response Relationship, Drug
- Gene Expression Profiling -- methods
- Gene Regulatory Networks -- drug effects
- Genotype
- Inhalation Exposure -- adverse effects
- Intracellular Signaling Peptides and Proteins -- genetics
- Lung -- drug effects
- Male
- Mice, Inbred C57BL
- Mice, Knockout
- Models, Animal
- Phenotype
- Signal Transduction -- drug effects
- Styrenes -- metabolism
- Time Factors
- Toxicogenetics -- methods
- Transcription Factors -- genetics
- Transcriptome -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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