Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures.
Andersen, Melvin E
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. [electronic resource] - Toxicology and applied pharmacology 11 2017 - 28-40 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2017.09.015 doi
Animals
Aryl Hydrocarbon Hydroxylases--genetics
Circadian Rhythm--drug effects
Circadian Rhythm Signaling Peptides and Proteins--genetics
Cytochrome P-450 CYP2B6--genetics
Cytochrome P-450 Enzyme System--deficiency
Cytochrome P450 Family 2--genetics
Dose-Response Relationship, Drug
Gene Expression Profiling--methods
Gene Regulatory Networks--drug effects
Genotype
Inhalation Exposure--adverse effects
Intracellular Signaling Peptides and Proteins--genetics
Lung--drug effects
Male
Mice, Inbred C57BL
Mice, Knockout
Models, Animal
Phenotype
Signal Transduction--drug effects
Styrenes--metabolism
Time Factors
Toxicogenetics--methods
Transcription Factors--genetics
Transcriptome--drug effects
Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling following 1-day and multi-week exposures. [electronic resource] - Toxicology and applied pharmacology 11 2017 - 28-40 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2017.09.015 doi
Animals
Aryl Hydrocarbon Hydroxylases--genetics
Circadian Rhythm--drug effects
Circadian Rhythm Signaling Peptides and Proteins--genetics
Cytochrome P-450 CYP2B6--genetics
Cytochrome P-450 Enzyme System--deficiency
Cytochrome P450 Family 2--genetics
Dose-Response Relationship, Drug
Gene Expression Profiling--methods
Gene Regulatory Networks--drug effects
Genotype
Inhalation Exposure--adverse effects
Intracellular Signaling Peptides and Proteins--genetics
Lung--drug effects
Male
Mice, Inbred C57BL
Mice, Knockout
Models, Animal
Phenotype
Signal Transduction--drug effects
Styrenes--metabolism
Time Factors
Toxicogenetics--methods
Transcription Factors--genetics
Transcriptome--drug effects