Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation. [electronic resource]
Producer: 20180730Description: 4308-4328 p. digitalISSN:- 1476-5381
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Autophagy -- drug effects
- Benzylisoquinolines -- pharmacology
- CRISPR-Cas Systems -- genetics
- Cell Differentiation -- drug effects
- Female
- Gene Knockout Techniques
- Humans
- K562 Cells
- Leukemia, Megakaryoblastic, Acute -- drug therapy
- Mice
- Mice, Nude
- Reactive Oxygen Species -- metabolism
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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