Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation.

Liu, Ting

Tetrandrine antagonizes acute megakaryoblastic leukaemia growth by forcing autophagy-mediated differentiation. [electronic resource] - British journal of pharmacology Dec 2017 - 4308-4328 p. digital

Publication Type: Journal Article

1476-5381

10.1111/bph.14031 doi


Animals
Antineoplastic Agents, Phytogenic--pharmacology
Autophagy--drug effects
Benzylisoquinolines--pharmacology
CRISPR-Cas Systems--genetics
Cell Differentiation--drug effects
Female
Gene Knockout Techniques
Humans
K562 Cells
Leukemia, Megakaryoblastic, Acute--drug therapy
Mice
Mice, Nude
Reactive Oxygen Species--metabolism
Xenograft Model Antitumor Assays