The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. [electronic resource]
Producer: 20180118Description: 212-224 p. digitalISSN:- 1476-5403
- Adolescent
- Animals
- Argonaute Proteins -- genetics
- Autophagy -- drug effects
- Autophagy-Related Protein-1 Homolog -- antagonists & inhibitors
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Child
- Child, Preschool
- Down-Regulation -- drug effects
- E2F1 Transcription Factor -- antagonists & inhibitors
- Female
- HEK293 Cells
- Humans
- Infant
- Infant, Newborn
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Leukemia, Promyelocytic, Acute -- genetics
- Male
- Membrane Proteins -- antagonists & inhibitors
- Mice
- Mice, SCID
- MicroRNAs -- antagonists & inhibitors
- Oncogene Proteins, Fusion -- antagonists & inhibitors
- Proteolysis -- drug effects
- Tretinoin -- pharmacology
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Publication Type: Journal Article
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