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The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway.

Chen, Zhen-Hua

The lncRNA HOTAIRM1 regulates the degradation of PML-RARA oncoprotein and myeloid cell differentiation by enhancing the autophagy pathway. [electronic resource] - Cell death and differentiation 02 2017 - 212-224 p. digital

Publication Type: Journal Article

ISSN: 1476-5403

Standard No.: 10.1038/cdd.2016.111 doi

Subjects--Topical Terms:
Adolescent
Animals
Argonaute Proteins--genetics
Autophagy--drug effects
Autophagy-Related Protein-1 Homolog--antagonists & inhibitors
Cell Differentiation--drug effects
Cell Line, Tumor
Child
Child, Preschool
Down-Regulation--drug effects
E2F1 Transcription Factor--antagonists & inhibitors
Female
HEK293 Cells
Humans
Infant
Infant, Newborn
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Leukemia, Promyelocytic, Acute--genetics
Male
Membrane Proteins--antagonists & inhibitors
Mice
Mice, SCID
MicroRNAs--antagonists & inhibitors
Oncogene Proteins, Fusion--antagonists & inhibitors
Proteolysis--drug effects
Tretinoin--pharmacology