Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors. [electronic resource]
Producer: 20170901Description: 479-490 p. digitalISSN:- 1476-5551
- Azepines -- pharmacology
- Cell Cycle -- drug effects
- Cell Cycle Proteins
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Chromatin -- genetics
- Cyclin-Dependent Kinase 9 -- metabolism
- E2F Transcription Factors -- metabolism
- Enhancer Elements, Genetic
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- Neoplasms -- genetics
- Nuclear Proteins -- metabolism
- Promoter Regions, Genetic
- Protein Binding
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Proteins c-myc -- genetics
- RNA Polymerase II -- metabolism
- Transcription Factors -- metabolism
- Transcription, Genetic
- Triazoles -- pharmacology
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Publication Type: Journal Article
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