Cu(II)-coumestrol interaction leads to ROS-mediated DNA damage and cell death: a putative mechanism for anticancer activity. [electronic resource]
Producer: 20171120Description: 15-27 p. digitalISSN:- 1873-4847
- Anticarcinogenic Agents -- chemistry
- Apoptosis -- drug effects
- Biomarkers -- metabolism
- Cell Survival
- Cells, Cultured
- Chelating Agents -- pharmacology
- Comet Assay
- Copper -- chemistry
- Coumestrol -- antagonists & inhibitors
- DNA Fragmentation -- drug effects
- Dietary Supplements
- Free Radical Scavengers -- pharmacology
- Humans
- Lipid Peroxidation -- drug effects
- Lymphocytes -- cytology
- Microscopy, Electron, Scanning
- Oxidative Stress -- drug effects
- Phytoestrogens -- antagonists & inhibitors
- Protein Carbonylation -- drug effects
- Reactive Oxygen Species -- agonists
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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