5-Fluorouracil inhibits dihydrofolate reductase precursor mRNA processing and/or nuclear mRNA stability in methotrexate-resistant KB cells. [electronic resource]
Producer: 19900119Description: 21413-21 p. digitalISSN:- 0021-9258
- Blotting, Northern
- Cell Nucleus -- drug effects
- Drug Resistance
- Exons
- Fluorouracil -- pharmacology
- Gene Amplification
- Genes
- Humans
- Introns
- KB Cells
- Kinetics
- Methotrexate -- pharmacology
- Plasmids
- RNA Precursors -- drug effects
- RNA Processing, Post-Transcriptional -- drug effects
- RNA, Messenger -- drug effects
- Restriction Mapping
- Tetrahydrofolate Dehydrogenase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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