Elevated Translation Initiation Factor eIF4E Is an Attractive Therapeutic Target in Multiple Myeloma. [electronic resource]
Producer: 20170615Description: 711-9 p. digitalISSN:- 1538-8514
- Animals
- Antineoplastic Agents -- pharmacology
- Biomarkers
- CCAAT-Enhancer-Binding Protein-beta -- genetics
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Disease Models, Animal
- Ectopic Gene Expression
- Eukaryotic Initiation Factor-4E -- antagonists & inhibitors
- Female
- Gene Expression
- Gene Expression Regulation, Neoplastic
- Gene Knockdown Techniques
- Genes, myc
- Humans
- Interferon Regulatory Factors -- genetics
- Mice
- Molecular Targeted Therapy
- Multiple Myeloma -- drug therapy
- Neovascularization, Pathologic -- drug therapy
- RNA Interference
- Signal Transduction -- drug effects
- Stromal Cells -- drug effects
- Tumor Burden -- drug effects
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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