Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids. [electronic resource]
Producer: 20161220Description: 4196460 p. digitalISSN:- 2314-6753
- Adult
- Apoptosis
- Body Mass Index
- Cells, Cultured
- Cytokines -- metabolism
- Drug Synergism
- Female
- Glucocorticoids -- administration & dosage
- Glucose -- chemistry
- Humans
- Immunosuppressive Agents -- therapeutic use
- Inflammation
- Insulin -- metabolism
- Insulin Secretion
- Islets of Langerhans -- drug effects
- Islets of Langerhans Transplantation
- Male
- Methylprednisolone -- chemistry
- Middle Aged
- Polymerase Chain Reaction
- RNA, Messenger -- metabolism
- Sirolimus -- administration & dosage
- Tacrolimus -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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