Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids.
Kloster-Jensen, Kristine
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids. [electronic resource] - Journal of diabetes research 2016 - 4196460 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2314-6753
10.1155/2016/4196460 doi
Adult
Apoptosis
Body Mass Index
Cells, Cultured
Cytokines--metabolism
Drug Synergism
Female
Glucocorticoids--administration & dosage
Glucose--chemistry
Humans
Immunosuppressive Agents--therapeutic use
Inflammation
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Islets of Langerhans Transplantation
Male
Methylprednisolone--chemistry
Middle Aged
Polymerase Chain Reaction
RNA, Messenger--metabolism
Sirolimus--administration & dosage
Tacrolimus--administration & dosage
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids. [electronic resource] - Journal of diabetes research 2016 - 4196460 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2314-6753
10.1155/2016/4196460 doi
Adult
Apoptosis
Body Mass Index
Cells, Cultured
Cytokines--metabolism
Drug Synergism
Female
Glucocorticoids--administration & dosage
Glucose--chemistry
Humans
Immunosuppressive Agents--therapeutic use
Inflammation
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Islets of Langerhans Transplantation
Male
Methylprednisolone--chemistry
Middle Aged
Polymerase Chain Reaction
RNA, Messenger--metabolism
Sirolimus--administration & dosage
Tacrolimus--administration & dosage